Gathering top mentions using Azithromycin and its activity against Lyme, Babesia, Bartonella, RMSF... We both used this. I used in IV.
"MACROLIDES include drugs like erythromycin, azalide, azithromycin, and clarithromycin. Given their ineffectiveness as a monotherapy, they have been utilized in combination therapies and are typically administered concurrently with hydroxychloroquine or amantadine, which raises vacuolar pH. This may affect your QT interval on an electrocardiogram, potentially causing arrhythmias. An EKG should be obtained before taking macrolides, especially if used in combination with other medications that can affect the QT interval (i.e., PPIs, SSRIs, many psychiatric medications, nausea medication like Zofran, or hydroxychloroquine). These drugs may also be given by intravenous, intramuscular, or subcutaneous injection, which has shown excellent results but typically causes abrupt Jarisch-Herxheimer reactions in patients."
"Two commonly prescribed antibiotics for tick-borne infections, doxycycline and azithromycin, cleared the persistent form of the bacteria at approximately the same levels as the drug-free control."
"Of the 25 combinations of antibiotics, four were able to completely eradicate stationary phase Bartonella in 24 hours – azithromycin/ciprofloxacin, azithromycin/methylene blue, rifampin/ciprofloxacin, and rifampin/methylene blue....
However, the azithromycin/ciprofloxacin, azithromycin/methylene blue, rifampin/ciprofloxacin, and rifampin/methylene blue combinations eradicated Bartonella in biofilms after six days."
Most rickettsial diseases respond well to antibiotics such as tetracycline, doxycycline and azithromycin.
Dr. Zhang’s 2020 study showed that the best combinations for persister Bartonella also are the strongest at removing biofilms. These combinations are: azithromycin and methylene blue; rifampin and methylene blue; azithromycin and ciprofloxacin; and rifampin and ciprofloxacin.
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